3种降压治疗方案的药物经济学评价
投稿时间:2017-07-20  修订日期:2017-11-03  点此下载全文
引用本文:张照伟,方甜子.3种降压治疗方案的药物经济学评价[J].药学实践杂志,2018,36(2):189~191
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作者单位
张照伟 浙江省金华市中心医院药剂科, 浙江 金华 321000 
方甜子 浙江省金华市中心医院药剂科, 浙江 金华 321000 
基金项目:金华市中心医院中青年科研启动基金(JY2017-2-13)
中文摘要:目的 应用药物经济学原理评价3种降压治疗方案,并找出最佳给药方案。方法 采用回顾性分析法,收集金华市中心医院120例高血压患者,分为3组,A组给予福辛普利钠片,B组给予缬沙坦胶囊,C组给予苯磺酸氨氯地平,疗程均为8周,观察患者的临床疗效并进行最小成本分析。结果 A、B、C 3组的有效率分别为90.7%、92.3%、92.1%,3组间无显著性差异(P>0.05)。3组的不良反应发生率分别为16.7%、7.7%、13.2%(P>0.05)。3组的人均总成本分别为287.3元、378.7元、320.4元(P<0.05)。结论 3组方案的疗效相似,从经济学角度来说,福辛普利钠(A组)的成本效果比最优。
中文关键词:福辛普利钠  缬沙坦  氨氯地平  最小成本分析
 
Pharmacoeconomic evaluation on three different anti-hypertensive treatments
Abstract:Objective To compare three different anti-hypertension therapeutic projects by pharmacoeconomic evaluation and to find out the best therapeutic project. Methods Retrospective study was used.120 patients with hypertension were randomly assigned to group A (fosinopril sodium),group B(valsartan),group C(amlodipine besylate tablet),the therapeutic effects were observed and were evaluated by cost minimization analysis. Results The total efficiency of A,B,C group were 90.7%, 92.3%, 92.1% (P>0.05) respectively. The incidence of adverse reaction were 16.7%,7.7%,13.2%(P>0.05) respectively. The costs were 287.3 yuan, 378.7 yuan and 320.4 yuan respectively. Conclution The effectiveness of the three groups was similar. In terms of pharmacoeconomics, group A was the best therapeutic project.
keywords:fosinopril sodium  valsartan  amlodipine besylate tablet  cost minimization analysis
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