知母皂苷成分的药理活性及作用机制研究进展
投稿时间:2017-06-15  修订日期:2017-09-20  点此下载全文
引用本文:刘艳平.知母皂苷成分的药理活性及作用机制研究进展[J].药学实践杂志,2018,36(1):24~29
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作者单位
刘艳平 上海市浦东新区人民医院, 上海 201200
同济大学附属杨浦医院, 上海 200090 
基金项目:上海市杨浦区卫计委资助项目(YP15Q05),2015年同济大学优秀青年人才培养计划(2015KJ049);上海市杨浦区中心医院院级课题(Se1201509)
中文摘要:知母作为传统中药,皂苷是其主要成分之一,具有广泛的活性和药理作用。近几年的文献报道,知母具有抗肿瘤、抗老年痴呆、改善学习记忆能力、抗凝血、抗血栓、降血糖、降血脂、抗抑郁、降血压等药理活性。从抗肿瘤作用,对中枢神经系统、心血管系统、内分泌系统的影响4个方面综述知母皂苷类成分的药理作用,为知母的进一步开发提供重要的依据。
中文关键词:知母皂苷  药理作用  研究进展
 
Progress on pharmacological activities and mechanism of Anemarrhena saponin
Abstract:As a traditional Chinese medicine, Anemarrhena saponin is one of the main components in Anemarrhena. Many pharmacological activities were reported in recent literatures, such as anti-tumor, anti-senile dementia, improving learning and memory, anti-clotting, anti-thrombus, reducing blood glucose and lipid, anti-depression, lowering blood pressure, and so on. In this paper, the pharmacological effects of the Anemarrhena saponin were summarized in four aspects which are anti-tumor, central nervous system, cardiovascular system and endocrine system to provide an important basis for further development of Anemarrhena.
keywords:Anemarrhena saponin  pharmacological activity  research progress
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