炎性细胞因子与膝骨关节炎诊断及治疗的最新研究进展
投稿时间:2017-08-04  修订日期:2017-09-11  点此下载全文
引用本文:袁颖超,廖秋菊.炎性细胞因子与膝骨关节炎诊断及治疗的最新研究进展[J].药学实践杂志,2018,36(1):9~12
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作者单位E-mail
袁颖超 首都医科大学宣武医院, 北京 100054  
廖秋菊 首都医科大学宣武医院, 北京 100054 qiujumm@sina.com 
基金项目:首都医科大学本科生科研创新项目(XSKY2016112)
中文摘要:膝骨关节炎(knee osteoarthritis,KOA)常见于中老年人,是以膝关节痛、肿胀、晨僵为主要特征的慢性退行性疾病,严重影响到患者的运动功能和身体健康。目前仍缺乏其早期诊断及治疗的方法。结合近年来KOA与炎性细胞因子相关性研究,探讨KOA与IL-1β、IL-6、TNF-α、TGF-β、IL-10、IL-17、IL-37等炎性因子的关系,为KOA的诊断和治疗提供理论依据。
中文关键词:膝骨关节炎  炎性细胞因子  诊断  治疗
 
Recent advances of inflammatory cytokines in the diagnosis and treatment of knee osteoarthritis
Abstract:Knee osteoarthritis (KOA) is a common chronic degenerative disease in the elderly population. It is characterized by knee-joint pain, swelling, morning stiffness and seriously affects the patients' motor function and physical health. So far, there is no early diagnosis and effective treatment for it. This paper outlined the recent researches on knee osteoarthritis and inflammatory cytokines to discuss the relationship between knee osteoarthritis and inflammatory factors such as IL-1β, IL-6, TNF-α, TGF-β, IL-10,IL-17 and IL-37, and provide the theoretical basis for the diagnosis and treatment of knee osteoarthritis.
keywords:knee osteoarthritis  inflammatory cytokines  diagnosis  treatment
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